Neuraminidase Inhibition Primes Short-Term Depression and Suppresses Long-Term Potentiation of Synaptic Transmission in the Rat Hippocampus

<div>Inhibition of NEU activity affects basal evoked excitatory synaptic transmission. (a) The arrangement of electrodes for recordings. fEPSPs were evoked by stimulation of Shaffer collaterals using concentric electrode (right) and recorded using a glass electrode (left) filled with extracellular solution placed in CA1 SR region. Scale bar, 0.5 mm. (b) Input-output curves show significant increase of the maximal fEPSP slope after suppression of NEU activity without the effect on the fiber volley (FV) amplitude.</div>

Neural Plasticity

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Figure 1

Figure 1: Neuraminidase Inhibition Primes Short-Term Depression and Suppresses Long-Term Potentiation of Synaptic Transmission in the Rat Hippocampus 

Figure 1 | Neuraminidase Inhibition Primes Short-Term Depression and Suppresses Long-Term Potentiation of Synaptic Transmission in the Rat Hippocampus 