Review Article

Eyes Open on Sleep and Wake: In Vivo to In Silico Neural Networks

Figure 1

(a) Nonrapid eye movement (NREM) sleep slow-wave activity (SWA) increases with time spent awake and decreases during sleep modified from [18]. (b) Calcium-dependent pathways regulate both scaling up and scaling down, to maintain a balance between excitation and inhibition modified from [19]. (c) Circadian modulation of synaptic plasticity modified from [20].
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