Value of Functionalized Superparamagnetic Iron Oxide Nanoparticles in the Diagnosis and Treatment of Acute Temporal Lobe Epilepsy on MRI

Figure 2

The distribution of iron particles in the hippocampus CA3 of models of TLE at 72 h post-SE after tail vein injection of particles. ((a)-(b)) Perl’s iron staining of saline group; ((c)-(d)) Perl’s iron staining of P-SPIONs group; ((e)-(f)) Perl’s iron staining of anti-IL-1β mAb-SPIONs group. ((a), (c), and (e)) Magnification 40; ((b), (d), and (f)) magnification 400; (g) shows bar graphs (mean ± SD, ) for the number of iron particles. versus saline group. versus saline group and anti-IL-1β mAb-SPIONs group.

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