Value of Functionalized Superparamagnetic Iron Oxide Nanoparticles in the Diagnosis and Treatment of Acute Temporal Lobe Epilepsy on MRI

Figure 4

Effect of anti-IL-1β mAb-SPIONs dependency on SE-induced neuronal cell loss of hippocampus CA3 at 72 h post-SE after injection. ((a)–(c)) The Nissl staining (400x); ((d)-(e)) the FJB staining (40x) showed FJB-positive cells; ((a), (d)) saline group; ((b), (e)) P-SPIONs group; ((c), (f)) anti-IL-1β mAb-SPIONs group. (g) Data (mean ± SD, ) present the number of the FJB-positive cells. versus saline group and P-SPIONs group; versus saline group.

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