Differential DNA Methylation of MicroRNA Genes in Temporal Cortex from Alzheimer’s Disease Individuals

Figure 3

Heat map of hypermethylated microRNAs versus predicted target pathways. The figure illustrates hierarchical clustering results for miRNAs (-axis) and pathways (-axis). The neuregulin receptor complex (ErbB) signaling pathway is clearly targeted by most investigated miRNAs. Image derived from DNA Intelligent Analysis- (DIANA-) miRPath using microT-CDS as the target prediction algorithm.