Direct Spinal Ventral Root Repair following Avulsion: Effectiveness of a New Heterologous Fibrin Sealant on Motoneuron Survival and Regeneration

Figure 5

Immunolabeling anti- and S100 in sciatic nerves, 4 weeks after ventral root avulsion and repair. Increased labeling is observed in all experimental groups as compared to control. S100: (a) intact nerve; (b, c, and d) ventral root avulsion (VRA); VRA followed by reimplantation with fibrin sealant derived from snake venom; ventral root avulsion followed by reimplantation with commercial fibrin sealant, respectively. p75: (e) intact nerve; (f, g, and h) ventral root avulsion (VRA); VRA followed by reimplantation with fibrin sealant derived from snake venom; ventral root avulsion followed by reimplantation with commercial fibrin sealant, respectively. (i) Quantification of S100 and labeling by the integrated density of pixels. Scale bar = 50 μm. Mean ± SE. .