Direct Spinal Ventral Root Repair following Avulsion: Effectiveness of a New Heterologous Fibrin Sealant on Motoneuron Survival and Regeneration

Figure 8

Paw print and walking profile, obtained with the CatWalk system, at 12 weeks after lesion. (a–c) Preoperative; (d–f) VRA Only; (g–i) VRA followed by reimplantation with fibrin sealant derived from snake venom; (j–l) ventral root avulsion followed by reimplantation with commercial fibrin sealant. Observe rats from reimplanted groups using the right paw, whereas the avulsed rat without root repair cannot control the lesioned limb. A significant restoration of weight-bearing capacity following avulsion and reimplantation with the fibrin sealants was also observed.