Inducing LTD-Like Effect in the Human Motor Cortex with Low Frequency and Very Short Duration Paired Associative Stimulation: An Exploratory Study

Figure 1

All investigated protocols. The order of the investigation is following the direction of the arrow which begins with 2-minute stimulation of 0.2 Hz and finishes at 1-minute stimulation of 1 Hz. Six different healthy volunteers were assigned to each protocol by the order of recruitment. We had to complete all 6 subjects in the same protocol before investigating the next protocol. Min = minute and = paired associative stimulation with interstimulus interval of 10 ms.