Models to Tailor Brain Stimulation Therapies in Stroke

Figure 4

Bimodal model based on inherent expressions of plasticity. We propose a bimodal model that explains how to empirically derive a cut-off that separates responders for stimulation of the traditional substrate-ipsilesional M1 (a) versus stimulation of an alternate substrate in the contralesional cortices (b). Our proposed bimodal model of paretic upper limb recovery: cut-off derived empirically (c).