Olfactory Bulb Field Potentials and Respiration in Sleep-Wake States of Mice

Figure 3

Breathing frequencies vary in freely moving animals. Transition from breathing to sniffing. (a) Raw signal. (b) Time-frequency distribution. (c) Power spectral density of the time periods indicated in (a). Power of olfactory bulb local field potential decreased with increasing respiration rate. (d) -scored peak power of plethysmography (PG, red; ; ; Friedman’s test), thermocouple (TC, gray; ; ; repeated measures ANOVA), and LFP in olfactory bulb (OB, black; ; ; repeated measures ANOVA). (e) Negative correlation between OB peak power and respiration rate during running (; ; , Pearson’s correlation). Group results in (d) and (e) are shown as mean ± standard error of the mean (SEM).