Dynamic Alterations of miR-34c Expression in the Hypothalamus of Male Rats after Early Adolescent Traumatic Stress

Figure 2

Anxiety-like behavior in the EPM test ( in each group). (a) Anxiety-like behavior of rats in the EPM test in adolescence. (b) Anxiety-like behavior of rats in the EPM test in adulthood. Ratio entry was defined as the total entries into the open arms divided by the total entries into any arm of the maze. Ratio time was defined as the total time spent in the open arms divided by the total time spent in any arm of the maze. Anxiety score was calculated as anxiety score = 1 − (ratio time + ratio entry/2). Values were expressed as mean ± SEM. and indicate and versus CON, respectively; and indicate and versus S, respectively.

(a)

(b)