Neural Plasticity / 2016 / Article / Tab 4 / Research Article
A Case-Control Study and Meta-Analysis Reveal BDNF Val66Met Is a Possible Risk Factor for PTSD Table 4 Individual studies with their respective odds ratios and 95% confidence intervals.
Study Val66Met Genotype counts Val/Val Val/Met Met/Met Zhang et al., 2006 [16 ] PTSD 69 (71.88) 26 (27.08) 1 (1.04)# No PTSD 166 (66.40) 74 (29.60) 10 (4.00) Odds ratio ( 1 0.845 (0.779) 0.241 (0.202) Lee et al., 2006 [30 ] PTSD 28 (26.17) 57 (53.27) 22 (20.56) No PTSD 48 (29.81) 82 (50.93) 31 (19.25) Odds ratio ( 1 1.192 (0.797) 1.217 (0.834) Valente et al., 2011 [28 ] All controls PTSD 48 (73.85) 15 (23.08) 2 (3.08)# No PTSD 584 (76.14) 169 (22.03) 14 (1.83) Odds ratio ( 1 1.080 (0.962) 1.738 (0.751) Controls only PTSD 48 (73.85) 15 (23.08) 2 (3.08)# No PTSD 555 (75.72) 164 (22.37) 14 (1.91) Odds ratio ( 1 1.058 (0.980) 1.652 (0.788) PTSD− only PTSD 48 (73.85) 15 (23.08) 2 (3.08)# No PTSD 29 (85.29) 5 (14.71) 0 (0.00)# Odds ratio ( 1 1.165 (0.482) 1.860 (0.316) Lyoo et al., 2011 [31 ] PTSD 10 (33.33) 15 (50.00) 5 (16.67) No PTSD 14 (38.89) 18 (50.00) 4 (11.11)# Odds ratio ( 1 1.167 (0.950) 1.750 (0.725) Pivac et al., 2012 [22 ] PTSD 235 (63.00) 126 (33.78) 12 (3.22) No PTSD 173 (65.28) 86 (32.45) 6 (2.26) Odds ratio ( 1 1.079 (0.884) 1.472 (0.687) Zhang et al., 2014 [27 ] PTSD 20 (47.62) 16 (38.10) 6 (14.29) No PTSD 294 (70.17) 104 (24.82) 21 (5.01) Odds ratio ( 1 2.262 (0.048) 4.200 (0.023) Li et al., 2016 [23 ] PTSD 39 (24.22) 80 (49.69) 42 (26.09) No PTSD 109 (29.46) 190 (51.35) 71 (19.19) Odds ratio ( 1 1.177 (0.725) 1.653 (0.120) Dretsch et al., 2016 [29 ] PTSD 28 (68.29) 8 (69.73) 5 (12.20) No PTSD 129 (69.73) 49 (26.49) 7 (3.78) Odds ratio ( 1 0.752 (0.755) 3.291 (0.129) Our study PTSD 99 (65.62) 46 (30.5) 6 (4.0) No PTSD 71 (67.0) 28 (26.4) 7 (6.6) Odds ratio ( 1 1.178 (0.811) 0.615 (0.639)
Note . # At least one cell count less than 5;
