[Retracted] Fractalkine Attenuates Microglial Cell Activation Induced by Prenatal Stress

Table 1

Effect of fractalkine on the expression of proinflammatory factors in the microglial cultures obtained from the control and prenatally stressed animals. The cells were treated with 50–200 ng/mL fractalkine. The expression of IL-1β, IL-18, TNF-α, IL-6, and CCL2 was measured after 24 hours of treatment. The qRT-PCR data are shown as the average fold change ± SEM; ; versus the control; # versus the stress group.

Gene	Control	Control + CX3CL1 50	Control + CX3CL1 100	Control + CX3CL1 200	Stress	Stress + CX3CL1 50	Stress + CX3CL1 100	Stress + CX3CL1 200
IL-1β	0.92 ± 0.05	0.95 ± 0.03	0.91 ± 0.06	0.92 ± 0.03	2.29 ± 0.12	2.13 ± 0.07	1.98 ± 0.05^#	1.73 ± 0.04^#
IL-18	0.80 ± 0.04	0.83 ± 0.02	0.89 ± 0.05	0.87 ± 0.03	1.35 ± 0.08	1.32 ± 0.04	1.29 ± 0.05	1.19 ± 0.04^#
TNF-α	0.64 ± 0.06	0.59 ± 0.08	0.54 ± 0.06	0.57 ± 0.09	1.37 ± 0.11	1.36 ± 0.12	1.17 ± 0.06	1.18 ± 0.03^#
IL-6	0.74 ± 0.08	0.77 ± 0.04	0.76 ± 0.03	0.76 ± 0.04	1.49 ± 0.07	1.48 ± 0.08	1.44 ± 0.04	1.19 ± 0.04^#
CCL2	1.01 ± 0.07	0.99 ± 0.05	1.03 ± 0.05	1.07 ± 0.04	1.42 ± 0.08	1.36 ± 0.04	1.26 ± 0.04	1.13 ± 0.03^#