Research Article
Human Auditory and Adjacent Nonauditory Cerebral Cortices Are Hypermetabolic in Tinnitus as Measured by Functional Near-Infrared Spectroscopy (fNIRS)
Table 1
Mean oxy-hemoglobin (HbO) concentration and standard error (parentheses) from region (ROI) and nonregion of interest (non-ROI) during silence (interstimulus rest; ISR) and stimulation (750 Hz, 8000 Hz, broadband noise; BBN) between tinnitus and control. The unit of concentration is micromolar (M). Independent and pairwise -test analyses were conducted as shown to assess hemodynamic response differences during the various experimental conditions within and between groups for all conditions. Relative values to zero reflect a hemodynamic response deactivation (negative) versus activation (positive) in hemodynamic response (statistically significant as compared to ISR in controls; as compared to ISR in tinnitus; as compared to BBN in tinnitus; and between tinnitus and controls; ).
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