Research Article
Nucleolar PARP-1 Expression Is Decreased in Alzheimer’s Disease: Consequences for Epigenetic Regulation of rDNA and Cognition
| | % of pyramidal cells nucleoli | Mean | -test |
| Control Alzheimer’s | PARP1(+)/Fib(+) | 58.80 29.74 | 0.039 () |
| Control Alzheimer’s | PARP1(+)/Fib(−) | 7.17 2.53 | 0.329 |
| Control Alzheimer’s | PARP1(−)/Fib(+) | 6.05 21.52 | 0.024 () |
| Control Alzheimer’s | Total PARP1(+) | 68.60 32.27 | 0.017 () |
| Control Alzheimer’s | Total Fib(+) | 64.85 51.69 | 0.242 |
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