Research Article

Nucleolar PARP-1 Expression Is Decreased in Alzheimer’s Disease: Consequences for Epigenetic Regulation of rDNA and Cognition

Table 2

CA1.

% of pyramidal
cells nucleoli
Mean-test

Control
Alzheimer’s
PARP1(+)/Fib(+)58.80
29.74
0.039 ()

Control
Alzheimer’s
PARP1(+)/Fib(−)7.17
2.53
0.329

Control
Alzheimer’s
PARP1(−)/Fib(+)6.05
21.52
0.024 ()

Control
Alzheimer’s
Total PARP1(+)68.60
32.27
0.017 ()

Control
Alzheimer’s
Total Fib(+)64.85
51.69
0.242

.