Research Article
Nucleolar PARP-1 Expression Is Decreased in Alzheimer’s Disease: Consequences for Epigenetic Regulation of rDNA and Cognition
| | % of pyramidal cells nucleoli | Mean | -test |
| Control Alzheimer’s | PARP1(+)/Fib(+) | 55.50 26.15 | 0.033 () |
| Control Alzheimer’s | PARP1(+)/Fib(−) | 5.68 4.58 | 0.830 |
| Control Alzheimer’s | PARP1(−)/Fib(+) | 1.74 24.78 | 0.031 () |
| Control Alzheimer’s | Total PARP1(+) | 61.18 30.73 | 0.051 |
| Control Alzheimer’s | Total Fib(+) | 57.24 50.56 | 0.450 |
|
|
.
|