Research Article

Nucleolar PARP-1 Expression Is Decreased in Alzheimer’s Disease: Consequences for Epigenetic Regulation of rDNA and Cognition

Table 3

CA4.

% of pyramidal
cells nucleoli
Mean-test

Control
Alzheimer’s
PARP1(+)/Fib(+)55.50
26.15
0.033 ()

Control
Alzheimer’s
PARP1(+)/Fib(−)5.68
4.58
0.830

Control
Alzheimer’s
PARP1(−)/Fib(+)1.74
24.78
0.031 ()

Control
Alzheimer’s
Total PARP1(+)61.18
30.73
0.051

Control
Alzheimer’s
Total Fib(+)57.24
50.56
0.450

.