mGlu5 Receptors and Relapse to Cocaine-Seeking: The Role of Receptor Trafficking in Postrelapse Extinction Learning Deficits

Figure 2

Intra-dlSTR infusion of MTEP does not attenuate context-primed relapse. (a) Mean infusions during the self-administration period did not differ between groups later given MTEP (5 μg) or vehicle during the relapse test. (b) Animals that self-administered cocaine relapsed upon placement in the self-administration context following abstinence while those receiving yoked-saline infusions did not. MTEP did not alter relapse. compared to Sal.

(a)

(b)