Emerging Synaptic Molecules as Candidates in the Etiology of Neurological Disorders

Figure 1

Molecular composition of a central chemical synapse. The image shows a typical excitatory synapse in the CNS. Pre- and postsynaptic proteins are organized in macromolecular functional complexes playing different roles in scaffolding, exocytosis, endocytosis, and signaling in their respective compartments. In addition, the most relevant adhesion molecules are represented.