A Subtle Network Mediating Axon Guidance: Intrinsic Dynamic Structure of Growth Cone, Attractive and Repulsive Molecular Cues, and the Intermediate Role of Signaling Pathways

<div>ADF/cofilin increases treadmilling of actin filaments. Treadmilling is fundamental for actin dynamic. In which process, actin filaments polymerize regularly at the barbed ends and depolymerize at the pointed ends. ADF/cofilin preferentially binds with the actin<sup>ADP</sup> subunits in the F-actin and increases the rate of depolymerization from the pointed end. The different quantities of the different species drawn are meant to give an idea of their relative concentration at steady state.</div>

Neural Plasticity

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Figure 3: A Subtle Network Mediating Axon Guidance: Intrinsic Dynamic Structure of Growth Cone, Attractive and Repulsive Molecular Cues, and the Intermediate Role of Signaling Pathways 

Figure 3 | A Subtle Network Mediating Axon Guidance: Intrinsic Dynamic Structure of Growth Cone, Attractive and Repulsive Molecular Cues, and the Intermediate Role of Signaling Pathways 