Research Article
Neuroplasticity and Neuroprotective Effect of Treadmill Training in the Chronic Mouse Model of Parkinson’s Disease
Table 1
Experimental groups used in the study.
| Group | Description of the treatment | Number of mice () | Treadmill training | The total duration of the experiment (weeks) |
| C (Control) | Saline (s.c.) and DMSO (i.p.) injections | 15 | NO | 10 | CTT (Control + treadmill training) | Saline (s.c.) and DMSO (i.p.) injections, 10 weeks of treadmill training | 11 | YES | 10 | M (MPTP) | MPTP (s.c.) and probenecid (i.p.) injections | 15 | NO | 10 | METT (MPTP + early onset treadmill training) | MPTP (s.c.) and probenecid (i.p.) injections 10 weeks of treadmill training started 1 week before the intoxication | 13 | YES | 10 | MLTT (MPTP + late-onset treadmill training) | MPTP (s.c.) and probenecid (i.p.) injections 10 weeks of treadmill training started immediately after the intoxication | 13 | YES | 16 |
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