Research Article

Neuroplasticity and Neuroprotective Effect of Treadmill Training in the Chronic Mouse Model of Parkinson’s Disease

Table 1

Experimental groups used in the study.

GroupDescription of the treatmentNumber of mice ()Treadmill trainingThe total duration of the experiment (weeks)

C
(Control)
Saline (s.c.) and DMSO (i.p.) injections15NO10
CTT
(Control + treadmill training)
Saline (s.c.) and DMSO (i.p.) injections, 10 weeks of treadmill training11YES10
M
(MPTP)
MPTP (s.c.) and probenecid (i.p.) injections15NO10
METT
(MPTP + early onset treadmill training)
MPTP (s.c.) and probenecid (i.p.) injections
10 weeks of treadmill training started 1 week before the intoxication
13YES10
MLTT
(MPTP + late-onset treadmill training)
MPTP (s.c.) and probenecid (i.p.) injections
10 weeks of treadmill training started immediately after the intoxication
13YES16