Alterations in Human Hippocampus Subregions across the Lifespan: Reflections on White Matter Structure and Functional Connectivity

Figure 3

Trends of hippocampal functional connectivity with age. (a) The FC results of GLM in the left hemisphere. The U-shaped trajectories of FC included aHipp.L-ACC.L, pHipp.L-ACC.L, and aHipp.L-Calcarine.L. The linear downward trajectory of FC included pHipp.L-Calcarine.L. (b) The FC results of GLM in the right hemisphere. The inverted U-shaped trajectories of FC included pHipp.R-MCC.R and pHipp.R-FFA.R. The linear upward trajectories of FC included aHipp.R-lOFC.R and pHipp.R-lOFC.R. The linear downward trajectory of FC included pHipp.R-mOFC.R. Orange plots represented the aHipp and blue plots the pHipp (“.L”: “left hemisphere”; “.R”: “right hemisphere”).

(a)

(b)