Infection-Induced Vulnerability of Perinatal Brain Injury

Figure 1

Diagram outlining infectious agents, TLRs, and major signaling pathways. Abbreviations: SE: S. epidermidis; GBS: group B streptococcus; LPT: lipopeptides. LPS: lipopolysaccharide; MyD88: myeloid differentiation primary response gene (88); TRIF: TIR domain-containing adaptor inducing interferon-β-mediated transcription factor; NF-κB: nuclear factor-KappaB; IRF: interferon regulatory factor; IP-10: interferon gamma-induced protein 10; IFN: interferon; TNF: tumor necrosis factor; IL-1: Interleukin -1.