Research Article

Short and Long-Term Analysis and Comparison of Neurodegeneration and Inflammatory Cell Response in the Ipsilateral and Contralateral Hemisphere of the Neonatal Mouse Brain after Hypoxia/Ischemia

Figure 13

Neutrophils quantification is done using image J software (NIH) and is evaluated at 3–72 hours and 7–100 days. The regions analysed were the hippocampus, medial/lateral third ventricle, caudate-putamen, neocortex, and thalamus. The quantity in the ipsilateral side is compared to the contralateral hemisphere. Significant changes are observed in the ipsilateral side of the hippocampus and caudate-putamen at 7 days after hypoxia while a decrease in number is observed after 3 hours in the ventricles and neocortex. There is no change in the thalamus. All values are represented as mean ± S.E.M and are corrected using Abercrombie correction method. Two-way ANOVA with Bonferroni post-hoc analysis is used to compare ipsilateral versus contralateral hemisphere at all time points and * , ** was considered significant.
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