|Table 1: Overview of studies: telomere length and depression.|
|: P < 0.05; **trend: P < 0.10.|
LTL: leukocyte telomere length; BTL: baseline telomere length; BTA: baseline telomerase activity; DST: dexamethasone suppression test; qPCR: quantitative polymerase chain reaction; qFISH: quantitative fluorescence in situ hybridization.
aUnclear if controls actually screened for MDD or controls answered in negative regarding previous diagnosis of MDD.
bFactors potentially affecting TL not evaluated/reported (stress, BMI, smoking status, physical activity, anti-inflammatory medications).
cHomogeneous group or ethnicity/races unreported.
dTesting unidirectional hypothesis (telomere length leads to development of depression).
eNo clinical diagnosis of depression (self-report of previous MDE or depression symptoms).
fBiomarkers measured at different time point than depression diagnosis.