Epigenetic Markers of Renal Function in African Americans

Table 1

Descriptive statistics of traits studied in GENOA African Americans.

	Total 𝑁=972	Males 𝑁=285	Females 𝑁=687	𝑃 value
	Mean (SD)	Mean (SD)	Mean (SD)
Estimated glomerular filtration rate (mL/min per 1.732 m^2)	85 (21)	83 (21)	86 (21)	0.0646^a
Age (years)	66 (8)	67 (8)	66 (8)	0.2179^a
Height (cm)	167 (9)	178 (6)	164 (6)	3.1𝐸−153^a
Weight (kg)	88 (18)	92 (17)	86 (18)	3.3𝐸−05^a
Waist circumference (cm)	104 (14)	104 (13)	103 (15)	0.7565^a
Hip circumference (cm)	116 (14)	110 (11)	118 (15)	1.3𝐸−17^a
Body mass index (kg/m^2)	31 (6)	29 (5)	32 (7)	1.7𝐸−15^a
C-reactive protein (mg/L)	0.7 (1)	0.6 (1)	0.7 (1)	0.00003^b
Fibrinogen (mg/dL)	369 (82)	354 (87)	376 (80)	0.0002^a
Homocysteine (𝜇mol/L)	11 (5)	12 (5)	10 (4)	4.7𝐸−09^b
Serum cholesterol (mg/dL)	204 (42)	192 (40)	209 (42)	1.8𝐸−08^a
Serum glucose (mg/dL)	113 (44)	116 (51)	112 (40)	0.3147^b
Serum triglycerides (mg/dL)	120 (64)	120 (74)	120 (60)	0.3292^b
Systolic blood pressure (mm Hg)	140 (21)	138 (21)	141 (22)	0.0396^a
Diastolic blood pressure (mm Hg)	78 (11)	80 (11)	78 (11)	0.0005^a
Combined high-density lipoprotein (mg/dL)	58 (18)	50 (15)	62 (18)	5.6𝐸−24^b
	𝑁 (%)	𝑁 (%)	𝑁 (%)	𝑃 value^c
Hypertension	802 (83)	228 (80)	574 (84)	0.1845
Diabetes	298 (31)	86 (30)	212 (31)	0.8334

^a𝑃 value from an independent 𝑡-test of means between males and females for normally distributed continuous variables.
^b𝑃 value from a two-sided 𝑍-test of a nonparametric Wilcoxon test for nonnormally distributed continuous variables.
^c𝑃 value from a chi-square test for categorical variables.