There is tremendous opportunity to expand clinically based research aimed at improving care quality with the strides made in electronic medical records, emphasis on consistent nurse sensitive data collected on patient populations, and the demand for evidence based practice. Yet, the key to advancing clinically based research, which is called ‘effectiveness science’, is creating clinical bridges between academia and practice to maximize discoveries. Such discoveries will aid the empirical understanding of what healthcare interventions work in real world settings, and why interventions work in some cases or practice settings and not others. Nurse researchers are in a unique position to lead effectiveness science through collaborations between academic environments and clinical settings.

We invite authors to submit original research, review articles, or exemplars of effectiveness science achieved through partnerships between academic and clinical settings. We are particularly interested in articles that illustrate partnerships that elucidate elements that enhance discovery and scientific applications in clinical settings. Potential topics include, but are not limited to:

• Essential characteristics of clinical-academic partnerships that enhance effectiveness science and/or its application to practice
• Testing effectiveness of healthcare interventions in a variety of practice settings
• Elucidating determinants of context of practice as they influence effectiveness of healthcare interventions
• New models and methods of creating partnerships between academia and practice
• The role of learners in building and applying effectiveness science
• Effectiveness science as part of the US NIH agenda
• International perspectives on readiness for effectiveness science
• Informatics and information system infrastructures to support effectiveness science
• Original research on patient outcomes effectiveness, translation science, comparative effectiveness, quality improvement, and dissemination and implementation

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/nrp/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable: