Environmentally Benign Mortar-Pestle-Induced Acylation and O-Alkylation of Aromatic and Heteroaromatic Compounds under Solvent-Free Micellar Conditions and Computation of Their Drug Likeliness Properties

Table 4

Reaction of 1-halo-2-methoxy naphthalene (2 mmol) with acylchlorides (2 mmol) using CTAB/CTAC as a catalyst.

Naphthalene	Acylchloride	Total; (%) Yield	Products ratio; (3 : 4)
		93	98 : 02
1a		90	98 : 02
1a		89	98 : 02
1a		92	98 : 02
1a		90	98 : 02
1a		93	98 : 02
1a		94	98 : 02
	2a	93	97 : 03
1b	2b	90	98 : 02
1b	2c	89	98 : 02
1b	2d	92	98 : 02
1b	2e	90	98 : 02
1b	2f	93	98 : 02
1b	2g	94	98 : 02

Duration of all reactions was 2 hr.