Genetics of Endometrial Cancers

Table 2

Genetics features of endometrial carcinoma.

	EEC	NEEC
Gain-of Function
K-ras	15–30%	0–5%
Her2/neu	10–20%	9–30%
𝛽-Catenin	31–47%	0–3%
Loss-of Function
PTEN	35–50%	10%
P53	10–20%	90%
Genomic instability (microsatellite)	20–40%	0-5%