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Obstetrics and Gynecology International
Volume 2011 (2011), Article ID 308609, 6 pages
Research Article

Quality of Life in Endometrial Cancer Survivors: What Does Obesity Have to Do with It?

1Division of Gynecologic Oncology, Greater Baltimore Medical Center/Johns Hopkins Hospital, Baltimore, MD 21204, USA
2Department of Obstetrics and Gynecology, University Hospitals Case Medical Center, Cleveland, OH 44106, USA
3Department of Obstetrics and Gynecology, Akron General Medical Center, Akron, OH 44302, USA
4Center for Science, Health and Society, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA
5Department of Obstetrics and Gynecology, Summa Akron City Hospital, Akron, OH 44309, USA

Received 29 April 2011; Revised 1 August 2011; Accepted 7 September 2011

Academic Editor: Diane C. Bodurka

Copyright © 2011 Amanda Nickles Fader et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objective. Most women with type I endometrial cancer (EC) are obese, increasing the risk of morbidity and mortality in this population. The study objective was to evaluate the impact of obesity on quality of life (QOL) and general health status in EC survivors with early-stage disease. Methods. A prospective ancillary analysis of stage I/II EC survivors. The association of BMI with QOL questionnaire variables measured with the functional assessment of cancer therapy (subscales: physical (PWB), functional (FWB), social, and emotional well-being) and the physical (PCS) and mental component summary subscales of the short-form medical outcomes survey was determined. Results. 152 women completed both questionnaires; 81% were obese. After multiple linear regression, BMI was inversely associated with PWB ( 𝑃 = . 0 0 1 ), FWB ( 𝑃 = 0 . 0 4 8 ), and PCS ( 𝑃 = . 0 0 1 ). Conclusions. Despite the good prognosis associated with early-stage EC, QOL, and physical health are not optimized in obese survivors. This paper highlights the importance of incorporating health-related QOL assessments and obesity interventions during the survivorship period.