About this Journal Submit a Manuscript Table of Contents
Obstetrics and Gynecology International
Volume 2011 (2011), Article ID 470795, 13 pages
http://dx.doi.org/10.1155/2011/470795
Review Article

Uterine Carcinosarcomas (Malignant Mixed Müllerian Tumours): A Review with Special Emphasis on the Controversies in Management

1Department of Pathology and Laboratory Medicine, University of Saskatchewan, Saskatoon, SK, Canada S7N 0W8
2Room 2868 G-Wing, Royal University Hospital, 103 Hospital Drive, Saskatoon, SK, Canada S7N 0W8

Received 20 July 2011; Accepted 2 August 2011

Academic Editor: Thomas Herzog

Copyright © 2011 Rani Kanthan and Jenna-Lynn Senger. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [18 citations]

The following is the list of published articles that have cited the current article.

  • Sree Harsha Tirumani, Vijayanadh Ojili, Alampady Krishna Prasad Shanbhogue, Najla Fasih, John G. Ryan, and Caroline Reinhold, “Current concepts in the imaging of uterine sarcoma,” Abdominal Imaging, vol. 38, no. 2, pp. 397–411, 2012. View at Publisher · View at Google Scholar
  • Brittany M. Rice, Nicholas W. Todd, Richard Jensen, Shannon M. Rush, and William Rogers, “Metastatic Calcaneal Lesion Associated with Uterine Carcinosarcoma,” The Journal of Foot and Ankle Surgery, 2013. View at Publisher · View at Google Scholar
  • Dinesh Pradhan, and Sambit K. Mohanty, “Uterine Tumors Resembling Ovarian Sex Cord Tumors,” Archives of Pathology & Laboratory Medicine, vol. 137, no. 12, pp. 1832–1836, 2013. View at Publisher · View at Google Scholar
  • Hyun Joo Lee, Hye-Jung Choi, Heung-Mo Yang, You Min Kim, Jeeyun Lee, Dongil Chio, BoKyung Kim, Yoon-La Choi, and Sung Joo Kim, “Establishment of Primary Xenograft Model From Newly Characterized Patient Extrauterine Carcinosarcoma,” International Journal of Gynecological Cancer, vol. 23, no. 9, pp. 1552–1560, 2013. View at Publisher · View at Google Scholar
  • Seema Husain, and Gokce Toruner, “AKT, EGFR, C-ErbB-2, and C-Kit Expression in Uterine Carcinosarcoma,” International Journal Of Gynecological Pathology, vol. 32, no. 5, pp. 493–500, 2013. View at Publisher · View at Google Scholar
  • Feng Chen, Chunjing Yu, Xuyang You, Boming Mi, and Weixing Wan, “Carcinosarcoma of the Uterine Corpus on 18F-FDG PET/CT in a Postmenopausal Woman With Elevated AFP,” Clinical Nuclear Medicine, vol. 39, no. 9, pp. 803–805, 2014. View at Publisher · View at Google Scholar
  • Siân Jones, Nicolas Stransky, Christine L. McCord, Ethan Cerami, James Lagowski, Devon Kelly, Samuel V. Angiuoli, Mark Sausen, Lisa Kann, Manish Shukla, Rosemary Makar, Laura D. Wood, Luis A. Diaz, Christoph Lengauer, and Victor E. Velculescu, “Genomic analyses of gynaecologic carcinosarcomas reveal frequent mutations in chromatin remodelling genes,” Nature Communications, vol. 5, pp. 5006, 2014. View at Publisher · View at Google Scholar
  • Kemal Gungorduk, Aykut Ozdemir, Ibrahim E. Ertas, Mehmet Gokcu, Elcin Telli, Tufan Oge, Ahmet Sahbaz, Sevil Sayhan, Muzaffer Sanci, Mehmet Harma, and Sinan Ozalp, “Adjuvant Treatment Modalities, Prognostic Predictors and Outcomes of Uterine Carcinosarcomas,” Cancer Research and Treatment, 2014. View at Publisher · View at Google Scholar
  • Fatemeh Homaei Shandiz, Sima Kadkhodayan, Zohre Yousefi Roodsari, Malihe Hsanzade Mofrad, Noorieh Sharifi Sistani, Majid Nabizadeh Marvast, and Mahbobe Sadeghei, “Prolonged Survival of a Patient With Pelvic Recurrence of Ovarian Malignant Mixed Mullerian Tumor After Chemoradiotherapy,” Iranian Red Crescent Medical Journal, vol. 16, no. 9, 2014. View at Publisher · View at Google Scholar
  • Y. Luo, Q. Yao, C. Ren, X. Ding, A. Hu, and C. Liu, “HPV infection status in cervical metaplastic carcinomas,” Journal of Clinical Pathology, vol. 68, no. 2, pp. 170–172, 2014. View at Publisher · View at Google Scholar
  • Grazia Artioli, Jacopo Wabersich, Ludwig Kathrin, Marina Paola Gardiman, Lucia Borgato, and Franco Garbin, “Rare uterine cancer: carcinosarcomas. Review from histology to treatment,” Critical Reviews in Oncology/Hematology, 2014. View at Publisher · View at Google Scholar
  • Andrzej Semczuk, Atanas Ignatov, Bogdan Obrzut, Jaume Reventos, and Tomasz Rechberger, “Role of p53 Pathway Alterations in Uterine Carcinosarcomas (Malignant Mixed Mullerian Tumors),” Oncology, vol. 87, no. 4, pp. 193–204, 2014. View at Publisher · View at Google Scholar
  • P. Hernández Mateo, R. Méndez Fernández, and E. Serrano Tamayo, “Sarcoma uterino frente a adenocarcinoma: ¿es posible distinguirlos mediante resonancia magnética?,” Radiología, 2015. View at Publisher · View at Google Scholar
  • Vidya Monappa, Ranjini Kudva, and Roumina Hasan, “Uterine malignant mixed mullerian tumor camouflaging as pelvic sarcoma,” Journal Of Cancer Research And Therapeutics, vol. 11, no. 4, pp. 997–999, 2015. View at Publisher · View at Google Scholar
  • Lei Zhang, David Shimizu, Jeffrey L. Killeen, Stacey A. Honda, Di Lu, Alexander Stanoyevitch, Fritz Lin, Beverly Wang, Edwin S. Monuki, and Michele Carbone, “Serous Carcinoma component championed by Heparin Binding-EGF Like Growth Factor (HB-EGF) Predisposing to Metastasis and Recurrence in Stage I Uterine Malignant Mixed Mullerian Tumor,” Human Pathology, 2016. View at Publisher · View at Google Scholar
  • Nicholas Mackrides, Parvin Ganjei-Azar, Roberto Perez, Tengijiao Cui, Norman Block, Andrew V. Schally, and Mehrdad Nadji, “GHRH Receptor Expression in Malignant Mixed Müllerian Tumors,” International Journal of Gynecological Pathology, vol. 35, no. 2, pp. 142–146, 2016. View at Publisher · View at Google Scholar
  • Hamdullah Sozen, Rumeysa Çiftçi, Dogan Vatansever, Samet Topuz, Ahmet Cem Iyibozkurt, Hamza Ugur Bozbey, Cenk Yaşa, Halime Çali, Ekrem Yavuz, Seden Kucucuk, Adnan Aydiner, and Yavuz Salihoglu, “Combination of adjuvant chemotherapy and radiotherapy is associated with improved survival at early stage type II endometrial cancer and carcinosarcoma,” Australian and New Zealand Journal of Obstetrics and Gynaecology, 2016. View at Publisher · View at Google Scholar
  • Hyun Ju Lee, Jeong-Yeol Park, Jong Jin Lee, Mi Hyun Kim, Dae-Yeon Kim, Dae-Shik Suh, Jong-Hyeok Kim, Yong-Man Kim, Young-Tak Kim, and Joo-Hyun Nam, “Comparison of MRI and 18F-FDG PET/CT in the preoperative evaluation of uterine carcinosarcoma,” Gynecologic Oncology, 2016. View at Publisher · View at Google Scholar