About this Journal Submit a Manuscript Table of Contents
Obstetrics and Gynecology International
Volume 2011 (2011), Article ID 548327, 6 pages
http://dx.doi.org/10.1155/2011/548327
Clinical Study

Postcesarean Thromboprophylaxis with Two Different Regimens of Bemiparin

1Obstetrics and Gynecology Department, San Cecilio University Hospital, Avenida Madrid No. 16, 18012 Granada, Spain
2Obstetrics and Gynecology Department, School of Medicine, University of Granada, Spain
3Methodology and Statistics Department, FIBAO and San Cecilio University Hospital, Granada, Spain

Received 30 July 2011; Revised 18 October 2011; Accepted 18 October 2011

Academic Editor: Enrique Hernandez

Copyright © 2011 Milagros Cruz et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Objectives. To compare the effectiveness of postcesarean thromboprophylaxis with two different regimens of bemiparin. Material and Methods. The study included 646 women with cesarean delivery in our hospital within a 1-year period, randomly assigned to one of two groups for prophylaxis with 3500 IU bemiparin once daily for 5 days or 3500 IU bemiparin once daily for 10 days. Results. There was one case of pulmonary embolism (first day following cesarean). An additional risk factor was present in 98.52% of the women, most frequently emergency cesarean, anemia, or obesity. The only risk factors for thromboembolic disease significantly related to pulmonary thromboembolism were placental abruption and prematurity. There were no differences in thromboembolic events among the two thromboprophylaxis regimens. Conclusions. Cesarean-related thromboembolic events were reduced in our study population due to the thromboprophylactic measures taken. Thromboprophylaxis with 3500 IU bemiparin once daily for 5 days following cesarean was sufficient to avoid thromboembolic events.