Table 1: Gene list of over- and underexpressed genes summarized by function. These dichotomously expressed genes reflect the gene expression heterogeneity among specimens.

Function Gene symbol Cell cycle CAV1 CCNA2 DDR2 E2F2 GPC3 GPC6 GTSE1 IFI16 MAD2L2 MAP2K6 NCAPH PTPN21 PTPN3 RBBP8 RPS6KA3 SLBP TGFBR3 TP53 TRMU Cell adhesion and migration CDH1 CDH3 CLDN3 CLDN4 CLEC10A HOXA10 HOXA11 HOXB2 HOXB3 HOXB4 HOXB5 HOXB6 HOXB7 HOXB8 HOXC4 HOXC5 HOXC6 IQGAP1 LGALS8 TGFBR3 Apoptosis IHPK2 BIRC5 BNIP3L BOK FAIM3 IL24 MAP2K6 MAPK10 PAK6 RBMS3 TP53 TPD52L1 WDR26 Infertility/fertility LEFTY2 PAK6 SPA17 SPAG1 Immunity BOC BST2 CD40 CEACAM1 CLEC10A ICAM1 IGSF11 JAK3 NR3C1 PVRL3 RIPK2 SIGLEC1 SIGLEC11 TNFSF13B TSC22D3 Cell structure ACTA2 ACTG2 ARHGAP25 ARL6IP5 CLDN5 CNKSR1 COL10A1 COL3A1 COL4A3 COL8A1 DCLK1 EMCN ESR1 HS6ST2 IQGAP1 ITGA11 ITGB8 KRT19 LAMA5 LAMB2 LAMC2 LAMC3 LTBP2 MMP26 NID2 PAK6 PCOLCE PPFIBP1 SGCE SIRPA SPC25 SPTBN1 TGFBR3 TNS1 VAPA Iron FTL Angiogenesis/invasion ADAMTS3 ANGPT1 ANGPTL1 C9ORF47 ITGA7 NRP1 NRP2 PROK1 S1PR3 TIMP1 TIMP4 Proliferation ADAMTS18 CLDN11 CREG1 DOK5 DUSP4 EHF GPC6 IFI16 MAP3K1 MAPRE2 NTRK2 PTPRB TRAF4 Steroid hormone regulation AKR1C1 AKR1C2 CPE CRYM CYP11A1 CYP2J2 CYP39A1 DIO2 ESR1 FST HSD11B1 NR3C1 PLTP PTGER3 PTGFR PTGIS RORA STAR VIPR2 Tumor suppressor DIRAS3 E2F2 FABP3 LYVE1 SMARCB1 Carcinogenesis DOCK4 ERBB3 ESR1 FN1 HLA-C JAZF1 IGK IGKC NBR1 RECK TBX2 Stress response BDNF