Table 2: Gene list summarizing the biosignature of the eutopic clade.

FunctionGene symbol

Cell cycleCDKN2APTGS2EGFRMDM2F2
BRCA2BTRC

Clotting/vascular integrityF2NOS1RHOAMMP1SP1

Cell adhesion and migrationCD36RHOAMMP1EGFRCDKN2A
F2JAG1PTGS2

ApoptosisMDM2BAT3BCL2L1IL17ARARA
CASP3BADAKAP13PTGS2EGFR
CDKN2AF2RHOA

Infertility/fertilityMMP1EGFRBRCA2BCL2L1PTGS2

ImmunityCD19CD68IL17AIL1RNRARA
CMA1CDKN2ABADCD36CNR2
MMP1

InflammationIL1RNIL17ACMA1PTGS2F2
CNR2

Cell structureKCNJ5TPM3RHOAEGFRF2
MMP1

CarcinogenesisTPM3KLK3EGFR

Angiogenesis/invasionJAG1KLK3PTGS2

Cell proliferationEGFRCDKN2AF2BRCA2MDM2
BTRCBADBCL2L1JAG1

OrganogenesisSP1TPM3MMP1EGFRBCL2L1
DRD2JAG1

Steroid hormone regulationRARARHOA

Tumor suppressorMDM2BAT3BRCA2NOS1

Stress responseFADS1NOS1RHOA

Protein ubiquitinationBTRCMDM2

Lipid metabolismABCA1FADS1PTGS2CD36

Dopamine receptorDRD2

Ion transportKCNJ5SP1RARADRD2PTGS2

Glucose homeostasisBADRHOA

Cell debris removalCD68CD36

Water and ion balanceDRD2

Cell differentiationFADS1JAG1SP1RHOA