Clinicopathological Role of Serum-Derived Hyaluronan-Associated Protein (SHAP)-Hyaluronan Complex in Endometrial Cancer
Figure 2
Disease-free survival in endometrial cancer patients was analyzed by the Kaplan-Meier method and log-rank test. The patients with the deeper myometrial invasion, poorly differentiated tumor, elevated serum level of the SHAP-HA complex, and elevated serum level of TIMP-1 had a significantly shorter disease-free survival. The maximal normal level in serum of the SHAP-HA complex in serum was determined as 4.7 U/mL for the SHAP-HA complex and as 212.9 ng/mL for TIMP-1, which were a value of the mean + 2SD in 50 healthy women.
