Expression and Prognostic Significance of Wnt7a in Human Endometrial Carcinoma
Table 4
Univariate survival analysis of PFS and OS in 70 patients with endometrial carcinoma.
Variable
Number
Estimated 5-year PFS (%)
-value
Estimated 5-year OS (%)
-value
Age (years)
0.198
0.881
≤60
22
68.2
77.3
>60
48
82.4
80.9
FIGO stage
<0.001
0.016
I + II
39
94.7
89.7
III + IV
31
56.1
66.7
Grade
0.007
0.016
G1
30
93.3
93.3
G2 + G3
40
65.3
69.2
Lymph node metastasis
0.011
0.010
Negative
49
85.0
87.8
Positive
21
60.0
60.0
Depth of myometrial invasion
0.005
0.051
≤1/2
31
92.9
90.3
>1/2
39
65.6
71.1
LVS involvement
<0.001
<0.001
Negative
44
92.9
95.5
Positive
26
50.6
52.0
Peritoneal cytology
<0.001
<0.001
Negative
53
92.2
92.5
Positive
17
27.3
37.5
Wnt7a
0.005
0.042
Negative
44
66.5
72.1
Positive
26
96.0
92.3
FIGO: International Federation of Gynecology and Obstertics; LVS: lymph vascular space; PFS: progression-free survival; OS: overall survival and *log-rank test.
