Circulating Unmetabolized Folic Acid: Relationship to Folate Status and Effect of Supplementation
Table 3
Baseline dietary and biochemical data for participants with detectable or undetectable (i.e., below the LOD) plasma concentrations of unmetabolized folic acid.
Undetectable ()
Detectable ()
Plasma folic acid (nmol/L)
—
8.8 (0.27–41.9)
—
Dietary folic acid (μg/day)
188.5 (56.8–380.0)
191.8 (70.6–395.8)
>0.99
Dietary total folate (μg DFE/day)
477.5 (181.9–849.2)
450.4 (231.9–979.4)
0.52
Plasma total folate (nmol/L)
48.7 (30.3–87.7)
43.7 (27.4–84.8)
0.27
RBC folate (nmol/L)
969.2 (761.0–1777.5)
1018.61 (710.3–2355.1)
0.88
a value, as determined by Wilcoxon-Mann-Whitney test (due to unequal sample sizes).