About this Journal Submit a Manuscript Table of Contents
Obstetrics and Gynecology International
Volume 2012 (2012), Article ID 850313, 7 pages
http://dx.doi.org/10.1155/2012/850313
Clinical Study

Phytoestrogens in Human Pregnancy

1Department of Obstetrics and Gynecology, University of Calgary, 1403 29 NW Street, Calgary, AB, Canada T2N 2T9
2Reproductive Biology Division, Department of Obstetrics and Gynecology, McMaster University, Hamilton, ON, Canada L8N 3Z5
3Alberta Centre for Toxicology, University of Calgary, Calgary, AB, Canada T2N 2T9

Received 1 July 2011; Revised 24 February 2012; Accepted 9 March 2012

Academic Editor: Everett Magann

Copyright © 2012 John Jarrell et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. CDC, Human Exposure Levels of Phytoestrogens, 2011.
  2. F. Petit, P. Le Goff, J. P. Cravédi, Y. Valotaire, and F. Pakdel, “Two complementary bioassays for screening the estrogenic potency of xenobiotics: recombinant yeast for trout estrogen receptor and trout hepatocyte cultures,” Journal of Molecular Endocrinology, vol. 19, no. 3, pp. 321–335, 1997. View at Publisher · View at Google Scholar · View at Scopus
  3. K. D Setchell, A. M. Lawson, S. P. Borriello, et al., “Lignan formation in man—microbial involvement and possible roles in relation to cancer,” Lancet, vol. 2, no. 8236, pp. 4–7, 1981.
  4. S. Vergne, K. Titier, V. Bernard et al., “Bioavailability and urinary excretion of isoflavones in humans: effects of soy-based supplements formulation and equol production,” Journal of Pharmaceutical and Biomedical Analysis, vol. 43, no. 4, pp. 1488–1494, 2007. View at Publisher · View at Google Scholar · View at Scopus
  5. H. Tapiero, G. Nguyen Ba, and K. D. Tew, “Estrogens and environmental estrogens,” Biomedicine and Pharmacotherapy, vol. 56, no. 1, pp. 36–44, 2002. View at Publisher · View at Google Scholar · View at Scopus
  6. M. K. Piskula, “Factors affecting flavonoids absorption,” BioFactors, vol. 12, no. 1-4, pp. 175–180, 2000. View at Scopus
  7. S. R. Stitch, J. K. Toumba, and M. B. Groen, “Excretion, isolation and structure of a new phenolic constituent of female urine,” Nature, vol. 287, no. 5784, pp. 738–740, 1980. View at Scopus
  8. S. Vergne, K. Titier, V. Bernard et al., “Bioavailability and urinary excretion of isoflavones in humans: effects of soy-based supplements formulation and equol production,” Journal of Pharmaceutical and Biomedical Analysis, vol. 43, no. 4, pp. 1488–1494, 2007. View at Publisher · View at Google Scholar · View at Scopus
  9. B. Balakrishnan, E. B. Thorstensen, A. P. Ponnampalam, and M. D. Mitchell, “Transplacental transfer and biotransformation of genistein in human placenta,” Placenta, vol. 31, no. 6, pp. 506–511, 2010. View at Publisher · View at Google Scholar · View at Scopus
  10. W. G. Foster, S. Chan, L. Platt, and C. L. Hughes, “Detection of phytoestrogens in samples of second trimester human amniotic fluid,” Toxicology Letters, vol. 129, no. 3, pp. 199–205, 2002. View at Publisher · View at Google Scholar · View at Scopus
  11. N. V. Soucy, H. D. Parkinson, M. A. Sochaski, and S. J. Borghoff, “Kinetics of genistein and its conjugated metabolites in pregnant Sprague-Dawley rats following single and repeated genistein administration,” Toxicological Sciences, vol. 90, no. 1, pp. 230–240, 2006. View at Publisher · View at Google Scholar · View at Scopus
  12. G. Degen, P. Janning, P. Diel, H. Michna, and H. Bolt, “Transplacental transfer of the phytoestrogen daidzein in DA/Han rats,” Archives of Toxicology, vol. 76, no. 1, pp. 23–29, 2002. View at Publisher · View at Google Scholar · View at Scopus
  13. C. R. Cederroth, J. Auger, C. Zimmermann, F. Eustache, and S. Nef, “Soy, phyto-oestrogens and male reproductive function: a review,” International Journal of Andrology, vol. 33, no. 2, pp. 304–316, 2010. View at Publisher · View at Google Scholar · View at Scopus
  14. W. G. Foster, S. Chan, L. Platt, and C. L. Hughes, “Detection of phytoestrogens in samples of second trimester human amniotic fluid,” Toxicology Letters, vol. 129, no. 3, pp. 199–205, 2002. View at Publisher · View at Google Scholar · View at Scopus
  15. J. Jarrell, S. Chan, R. Hauser, and H. Hu, “Longitudinal assessment of PCBs and chlorinated pesticides in pregnant women from Western Canada,” Environmental Health, vol. 4, 2005. View at Publisher · View at Google Scholar · View at Scopus
  16. W. G. Foster, S. Chan, L. Platt, and C. L. Hughes, “Detection of phytoestrogens in samples of second trimester human amniotic fluid,” Toxicology Letters, vol. 129, no. 3, pp. 199–205, 2002. View at Publisher · View at Google Scholar · View at Scopus
  17. D. B. Clarke, A. S. Lloyd, N. P. Botting, M. F. Oldfield, P. W. Needs, and H. Wiseman, “Measurement of intact sulfate and glucuronide phytoestrogen conjugates in human urine using isotope dilution liquid chromatography-tandem mass spectrometry with [13C3]isoflavone internal standards,” Analytical Biochemistry, vol. 309, no. 1, pp. 158–172, 2002. View at Publisher · View at Google Scholar · View at Scopus
  18. H. Wiseman, K. Casey, E. A. Bowey et al., “Influence of 10 wk of soy consumption on plasma concentrations and excretion of isoflavonoids and on gut microflora metabolism in healthy adults,” American Journal of Clinical Nutrition, vol. 80, no. 3, pp. 692–699, 2004. View at Scopus
  19. C. R. Cederroth, J. Auger, C. Zimmermann, F. Eustache, and S. Nef, “Soy, phyto-oestrogens and male reproductive function: a review,” International Journal of Andrology, vol. 33, no. 2, pp. 304–316, 2010. View at Publisher · View at Google Scholar · View at Scopus
  20. J. M. Hamilton-Reeves, G. Vazquez, S. J. Duval, W. R. Phipps, M. S. Kurzer, and M. J. Messina, “Clinical studies show no effects of soy protein or isoflavones on reproductive hormones in men: results of a meta-analysis,” Fertility and Sterility, vol. 94, no. 3, pp. 997–1007, 2010. View at Publisher · View at Google Scholar · View at Scopus
  21. G. Degen, P. Janning, P. Diel, H. Michna, and H. Bolt, “Transplacental transfer of the phytoestrogen daidzein in DA/Han rats,” Archives of Toxicology, vol. 76, no. 1, pp. 23–29, 2002. View at Publisher · View at Google Scholar · View at Scopus