Cervical Length Measurement for the Prediction of Preterm Birth in Symptomatic Women with a Twin Pregnancy: A Systematic Review and Meta-Analysis

Table 2

Observed sensitivity and specificity for each study with 95% CI.

Study	𝑁	Cut-off CL	Cut-off PTB	TP	FP	FN	TN	Sens.	95% CI	Spec.	95% CI	PPV	NPV	LR+	LR−
Fuchs	87	25	<7 days	19	47	0	21	1.0	0.83–1.0	0.31	0.31–0.43	0.29	1.0	1.5	0
Crane	26	30	34	5	9	0	12	1.0	0.57–1.0	0.57	0.37–0.76	0.36	1.0	2.3	0
Crane	26	30	37	12	7	4	3	0.75	0.51–0.90	0.30	0.11–0.60	0.63	0.43	1.1	0.83
Gonzalez	66	20	34	13	12	15	26	0.46	0.29–0.64	0.68	0.53–0.81	0.52	0.63	1.5	0.78
Gonzalez	66	30	34	21	27	7	11	0.75	0.57–0.87	0.29	0.17–0.45	0.44	0.61	1.1	0.86
Gonzalez	66	30	37	44	4	16	2	0.73	0.61–0.83	0.33	0.09–0.70	0.92	0.11	1.1	0.80
Venditelli	26	30	37	13	6	2	5	0.87	0.62–0.96	0.46	0.21–0.72	0.68	0.71	1.6	0.29
Yoshizato	21	25	37	12	8	0	1	1.0	0.76–1.0	0.11	0.02–0.55	0.60	1.0	1.1	0

TP: true positive; FP: false positive; FN: false negative; TN: true negative; PPV: positive predictive value; NPV: negative predictive value; LR+: likelihood ratio positive; LR−: likelihood ratio negative.