Clinical Study

An Elevated Maternal Plasma Soluble fms-Like Tyrosine Kinase-1 to Placental Growth Factor Ratio at Midtrimester Is a Useful Predictor for Preeclampsia

Table 2

Maternal plasma concentrations of sFlt-1, PlGF, and sFlt-1/PlGF ratio in women who developed preeclampsia and in controls.

VariablePreeclampsia patients ( )Matched controls ( ) value

sFlt-1 (pg/mL)4490 (1080)2590 (419)<0.0001
PlGF (pg/mL)98 (35)186 (52)<0.0001
sFlt-1/PlGF ratio44.6 (16.2)14.4 (6.1)<0.0001

sFlt-1: soluble fms-like tyrosine kinase 1; PlGF: placental growth factor.
Data are presented as median (interquartile range).
value < 0.05 is significant.