HIV and Menopause: A Systematic Review of the Effects of HIV Infection on Age at Menopause and the Effects of Menopause on Response to Antiretroviral Therapy

Table 1

Studies available through 2012 evaluating age at menopause in HIV-infected women.

Authors; (year)	Country	Number of women for analysis	Percent of participants who were black/African American or Hispanic/Latina	HIV status	𝑁	Number of women with menopause	Age at onset of menopause (years)	𝑃 value
Clark et al. (2000) [26]	United States	52	43% (black/AA); 15% (Hispanic)	Infected; Uninfected	52; 0	26 (50.0%); NA	47 (IQR 32–57) (mean); NA	NA
Cejtin et al. (2004) [35]	United States	1335	NR	Infected; Uninfected	1063; 272	NR; NR	47.7 (mean); 48.0	NS
Fantry et al. (2005) [17]	United States	120	95% (black/AA)	Infected; Uninfected	120; 0	NR; NA	50.0 (IQR 49.3–53.0) (median); NA	NA
Schoenbaum et al. (2005) [16]	United States	571	49% (black/AA); 40% (Hispanic)	Infected; Uninfected	302; 269	62 (20.5%); 40 (14.9%)	46.0 (IQR 39.0–49.0); 47.0 (IQR 44.5–48.0)	0.03
Ferreira et al. (2007) [25]	Brazil	251	NA	Infected; Uninfected	96; 155	NR; NR	47.5 (median); NR	NR
de Pommerol et al. (2011) [18]	France	404	NA	Infected; Uninfected	404; 0	69 (17.1%); NA	49 (IQR 40–50) (median); NA	NA

AA: African American, IQR: interquartile range, NA: not applicable, NR: not reported, NS: not significant.