Table 5: The results of group and subgroup analyses according to the comparison of mean WHAQ scores changes within groups.

Within group
Repeated ANOVA
PremenstrualMenstrual Postmenstrual
Mean WHAQ scores*DSG
(±SE)
Sig.DRSP
(±SE)
Sig.DSG
(±SE)
Sig.DRSP
(±SE)
Sig.DSG
(±SE)
Sig.DRSP
(±SE)
Sig.

Baseline–3rd cycle0.42 ± 0.410.3076.56 ± 0.790.000−0.69 ± 0.340.0464.44 ± 0.760.000−0.11 ± 0.260.6721.36 ± 0.340.000
TotalBaseline–6th cycle3.24 ± 0.770.00013.71 ± 1.250.0001.73 ± 0.630.0089.93 ± 0.960.0000.47 ± 0.300.1321.87 ± 0.450.000
3rd cycle–6th cycle2.82 ± 0.650.0007.16 ± 0.910.0002.42 ± 0.580.0005.49 ± 0.550.0000.58 ± 0.270.0410.51 ± 0.250.050
Baseline–3rd cycle0.42 ± 0.190.0312.31 ± 0.450.0000.04 ± 0.170.8001.58 ± 0.450.0010.04 ± 0.130.7360.58 ± 0.210.008
Negative effectBaseline–6th cycle2.16 ± 0.440.0005.82 ± 0.580.0001.49 ± 0.330.0004.36 ± 0.500.0000.38 ± 0.180.0391.31 ± 0.230.000
3rd cycle–6th cycle1.73 ± 0.400.0003.51 ± 0.430.0001.44 ± 0.300.0002.78 ± 0.390.0000.33 ± 0.150.0340.73 ± 0.180.000
Baseline–3rd cycle0.20 ± 0.130.1301.87 ± 0.270.000−0.64 ± 0.170.0001.20 ± 0.310.000−0.20 ± 0.120.1070.40 ± 0.140.005
Water retentionBaseline–6th cycle0.844 ± 0.320.0123.53 ± 0.460.000−0.36 ± 0.370.3452.29 ± 0.390.000−0.02 ± 0.140.8720.53 ± 0.180.005
3rd cycle–6th cycle0.644 ± 0.310.0401.67 ± 0.320.0000.29 ± 0.310.3651.09 ± 0.250.0000.18 ± 0.120.1320.13 ± 0.110.225
Baseline–3rd cycle0.38 ± 0.180.0362.58 ± 0.380.0000.60 ± 0.210.0072.24 ± 0.400.0000.11 ± 0.140.4170.51 ± 0.180.006
Impaired concentrationBaseline–6th cycle1.22 ± 0.340.0014.91 ± 0.630.0001.36 ± 0.290.0004.16 ± 0.520.0000.36 ± 0.170.0410.82 ± 0.180.000
3rd cycle–6th cycle0.84 ± 0.280.0052.33 ± 0.460.0000.76 ± 0.230.0021.91 ± 0.290.0000.24 ± 0.160.1400.31 ± 0.110.009
Baseline–3rd cycle−0.11 ± 0.140.4170.76 ± 0.120.000−0.04 ± 0.100.6430.69 ± 0.140.000−0.18 ± 0.110.1030.16 ± 0.080.051
Increased appetiteBaseline–6th cycle−0.20 ± 0.180.2841.02 ± 0.180.0000.16 ± 0.180.3991.18 ± 0.180.000−0.07 ± 0.120.5700.16 ± 0.100.128
3rd cycle–6th cycle−0.09 ± 0.130.4860.27 ± 0.130.0500.20 ± 0.140.1620.49 ± 0.140.0010.11 ± 0.090.2290.00 ± 0.081.00
Baseline–3rd cycle−0.47 ± 0.120.000−0.96 ± 0.120.000−0.58 ± 0.120.000−1.27 ± 0.160.0000.11 ± 0.120.375−0.29 ± 0.150.068
Feeling of well beingBaseline–6th cycle−0.78 ± 0.130.000−1.58 ± 0.130.000−0.84 ± 0.160.000−1.98 ± 0.160.000−0.18 ± 0.150.242−0.96 ± 0.110.000
3rd cycle–6th cycle−0.31 ± 0.120.015−0.62 ± 0.120.000−0.27 ± 0.130.038−0.71 ± 0.170.000−0.29 ± 0.150.063−0.67 ± 0.140.000
Baseline–3rd cycle0.00 ± 0.000.00 ± 0.000.00 ± 0.000.00 ± 0.000.00 ± 0.000.00 ± 0.00
Undesirable hair changesBaseline–6th cycle0.00 ± 0.000.00 ± 0.000.00 ± 0.000.00 ± 0.000.00 ± 0.000.00 ± 0.00
3rd cycle–6th cycle0.00 ± 0.000.00 ± 0.000.00 ± 0.000.00 ± 0.000.00 ± 0.000.00 ± 0.00

 DSG: desogestrel and DRSP: drospirenone.
 *Mean WHAQ scores were calculated from summed scores of all the subjects divided by the number of subjects.