Research Article

The Natural History of Uterine Leiomyomas: Light and Electron Microscopic Studies of Fibroid Phases, Interstitial Ischemia, Inanosis, and Reclamation

Figure 7

Collagen production by tumor myocytes. (a) In this Masson trichrome stained section, the interstitium of the tumor fascicle is expanded by abundant blue collagen that separates the red staining fibroid myocytes. No interspersed fibroblasts are noted in the blue collagenous stroma, indicating that the stromal matrix has been produced by the tumor myocytes themselves. (b) Many of the myocytes in the central portion of this Masson trichrome stained section are reduced in size (short arrows) in comparison with those above and below (long arrows). These appear to be atrophic cells, although the possibility of artifactual tangential sectioning cannot be excluded. Original objective magnification of (a) and (b): 40x.
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