828165.fig.005
Figure 5: BIBF1120+paclitaxel modifies G2/M checkpoint controllers to induce transition into M phase. The effect of 1 μM BIBF1120, 14 nM paclitaxel, and combination treatment (24 h) on the posttranslational modification of cell cycle regulators was examined by Western blotting. *denotes slower-migrating CDC25C, indicative of activating phosphorylation.