Chlamydia trachomatis Antibody Testing in Vaginal Mucosal Material versus Blood Samples of Women Attending a Fertility Clinic and an STI Clinic
Table 1
Number and proportion of samples with detectable IgG or IgA Chlamydia antibodies per subgroup, determined in serum and vaginal swab samples from women seen at the STI clinic and at the fertility clinic.
Serum-IgA
%
Serum-IgG
%
Swab-IgA
%
Swab-IgG
%
STI clinic
116
13
93
(14%)
36
100
(36%)
20
107
(19%)
40
102
(39%)
PCR
+
33
9
24
(38%)
29
31
(94%)
12
29
(41%)
15
31
(48%)
−
83
4
69
(6%)
7
69
(10%)
8
78
(10%)
25
71
(35%)
Ct history
+
11
1
11
(9%)
8
11
(73%)
2
8
(25%)
2
10
(20%)
−
115
12
81
(15%)
28
88
(32%)
18
98
(18%)
38
92
(41%)
Symptoms
+
24
2
17
(12%)
11
20
(55%)
4
22
(18%)
6
19
(32%)
−
116
11
76
(14%)
25
80
(31%)
16
85
(19%)
34
83
(41%)
Condom use
+
34
3
28
(11%)
8
31
(26%)
6
34
(18%)
8
21
(38%)
−
74
9
59
(15%)
27
62
(44%)
14
65
(22%)
31
68
(46%)
Partners < 6 months
0 or 1
41
0
31
(0%)
8
32
(25%)
4
38
(11%)
12
34
(35%)
2
28
5
28
(18%)
8
28
(29%)
6
24
(25%)
10
27
(37%)
3 or more
47
8
34
(24%)
20
40
(50%)
10
45
(22%)
18
41
(44%)
ethnicities
Dutch
106
11
84
(13%)
32
92
(35%)
14
97
(14%)
33
92
(36%)
non-Dutch
10
2
9
(22%)
4
8
(50%)
6
10
(60%)
7
10
(70%)
Fertility clinic
77
n.a.
25
77
(32%)
8
77
(10%)
34
77
(44%)
Tubal pathology
+
9
8
9
(89%)
4
9
(44%)
5
9
(56%)
−
70
17
68
(25%)
4
64
(6%)
29
68
(43%)
Ct history
+
21
17
21
(81%)
7
21
(33%)
14
21
(67%)
−
56
8
56
(14%)
1
56
(2%)
20
56
(36%)
Percentages in bold indicate significant differences in proportion positive for that determinant.
