Resveratrol, Acetyl-Resveratrol, and Polydatin Exhibit Antigrowth Activity against 3D Cell Aggregates of the SKOV-3 and OVCAR-8 Ovarian Cancer Cell Lines

Figure 6

In SKOV-3 cell aggregates, the phosphorylation of Her-2 (A) and EGFR (B) was significantly reduced at higher concentrations of polydatin. The total expression of EGFR was significantly reduced with 100 μM polydatin (D). There was no effect on Erk1/2 (E). refers to statistically significant as value less than 0.05 compared to the control.

(a)

(b)