Research Article

Prognostic Value of Residual Disease after Interval Debulking Surgery for FIGO Stage IIIC and IV Epithelial Ovarian Cancer

Table 1

Baseline characteristics.

All patients ()PDS ()IDS ()

Age; mean (SD)61.5 (10.7)59.4 (31–86)62.5 (29–83)
WHO performance status, number (%)
 0310 (45.0)122 (53.7)188 (40.7)
 1218 (31.6)63 (27.7)155 (33.5)
 253 (7.7)13 (5.6)40 (8.7)
 39 (1.3)2 (0.1)7 (1.5)
 Missing99 (14.4)27 (11.9)72 (15.6)
ASA-score, number (%)
 1198 (28.7)62 (27.4)136 (29.4)
 2370 (53.7)119 (52.4)251 (54.2)
 388 (12.8)35 (15.4)53 (11.5)
 Missing34 (4.9)11 (4.8)23 (4.9)
FIGO stage, number (%)
 IIIC543 (78.8)209 (92.1)334 (72.3)
 IV146 (21.2)18 (7.9)128 (27.7)
Histologic type, number (%)
 Serous 502 (72.9)156 (68.7)346 (74.8)
 Mucinous 24 (3.5)12 (5.3)12 (2.6)
 Endometrioid 47 (6.8)29 (12.8)18 (3.9)
 Clear cell 20 (2.9)11 (4.8)9 (2.0)
 Undifferentiated 86 (12.5)12 (5.3)74 (16.1)
 Mixed/other 10 (1.5)7 (3.0)3 (0.6)
Histologic grade, number (%)
 Well differentiated 32 (4.6)15 (6.6)17 (3.7)
 Moderately differentiated 103 (14.9)47 (20.7)56 (12.1)
 Poorly differentiated 373 (54.1)141 (62.1)232 (50.2)
 Missing 181 (26.3)24 (10.6)157 (34.0)
CA 125 before treatment; median (range)908.0 (12–67448)807.5 (12–67448)1041 (15–42077)
Ascites at surgery (ml); median (range)500 (0–70000)200 (0–12000)500 (0–70000)
Cycles of chemotherapy6 (0–13)6 (0–9)6 (0–13)
Type of chemotherapy
 Carboplatin/paclitaxel 641 (93)197 (87)444 (96)
 Multidrug without platinum10 (1.5)3 (1)7 (2)
 Single drug platinum27 (3.9)17 (8)10 (2)
 No chemotherapy received8 (1.2)8 (4)0 (0.0)
 Missing 3 (0.4)2 (1)1 (0)