A Reappraisal of Women’s Health Initiative Estrogen-Alone Trial: Long-Term Outcomes in Women 50–59 Years of Age

Figure 2

Outcomes for women 50-59 years of age at trial entry, conjugated equine estrogens (CEE) versus placebo, cumulative long-term follow-up (13 years), and WHI Estrogen-Alone Trial. Global index represents the first event for each participant from among the following: coronary heart disease (nonfatal MI or coronary death), stroke, pulmonary embolism, breast cancer, colorectal cancer, hip fracture, or death due to other causes. CEE: conjugated equine estrogens; CHD: coronary heart disease; CI: confidence interval; DVT: deep vein thrombosis; FU: follow-up; Fx: fracture; MI: myocardial infarction; P: placebo; PE: pulmonary embolus; WHI: Women’s Health Initiative. Source for outcomes: [3].