Research Article
A Reappraisal of Women’s Health Initiative Estrogen-Alone Trial: Long-Term Outcomes in Women 50–59 Years of Age
Table 3
Number of women needed to treat (randomized to CEE) to prevent one woman from developing a myocardial infarction or global index event, women aged 50–59 years at trial entry, Women’s Health Initiative Estrogen-Alone Trial, and cumulative long-term outcomes.
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A number needed to treat analysis for MI and global index for the intervention phase for women aged 50–59 years did not show a statistically significant difference in outcomes for the CEE versus placebo group. aA participant is counted as having a global index event if there is the diagnosis of one or more of the following occurring after randomization: coronary heart disease (nonfatal MI or coronary death), stroke, pulmonary embolism, invasive breast cancer, colorectal cancer, hip fracture, or death due to other causes. CEE: conjugated equine estrogens; CI: confidence interval; MI: myocardial infarction; NS: not significant. Derived (as per Methods Section) from data provided in [3]. |