Safety and Efficacy of Ferric Carboxymaltose in Anemic Pregnant Women: A Retrospective Case Control Study

Table 3

Pregnancy outcomes in cases and controls.

Pregnancy outcome	Case group ()	Control group ()	value
Hospital admission ()^†	27 (42%)	20 (31%)	0.13
ICU admission ()^†	1 (2%)	2 (3%)	0.51
IUGR ()^†	2 (3%)	5 (8%)	0.30
Hypertension/preeclampsia ()^†	8 (13%)	9 (14%)	0.36
Placental abruption ()^†	1 (2%)	0 (0%)	0.22
Median Hb at delivery, g/dL ()^†	10.7 [9.8; 11.5]	10.8 [9.8; 11.8]	0.76
Median Hb at delivery, mmol/L ()^†	6.7 [6.1; 7.1]	6.7 [6.1; 7.3]	0.76
Unknown Hb at delivery	18 (28%)	16 (25%)
Major adverse outcome ()^†
Maternal only	3 (5%)	4 (6%)	0.50
Fetal only	5 (8%)	5 (8%)
Maternal and fetal	2 (3%)	6 (9%)
Minor maternal outcome^‡ ()^†	23 (36%)	18 (28%)	0.36
Need for transfusion of blood products ()^†	2 (3%)	3 (5%)	0.20
Gestational age at delivery, weeks ()^†	39.2 [38.0; 40.3]	39.1 [36.7; 39.9]	0.18
Mode of delivery ()^†
Spontaneous vaginal	46 (72%)	39 (61%)	0.29
Assisted vaginal	2 (3%)	5 (8%)
Primary Caesarean	9 (14%)	12 (19%)
Secondary Caesarean	5 (8%)	8 (13%)
Blood loss during delivery, mL ()^†	300 [200; 400]	300 [200; 538]	0.64
Fetal weight, g ()^†
Singleton babies	3235 [3025; 3565]	3210 [2710; 3500]	0.64
Twin babies	2400 [1872; 2721]	2343 [1675; 2618]	0.33
Apgar score ()^†
Singleton babies	10 [10; 10]	10 [9; 10]	0.73
Twin babies	9 [7; 10]	9 [7; 10]	0.92

Data shown as median [IQR] or (%); ^†patients with available data (for remainder of study population not reported/unknown).
^‡Minor maternal outcomes: malaise (2 in case group), abdominal pain (3 in case group, 2 in control group), nausea and vomiting of pregnancy (NVP) (3 in case group, 3 in control group), premature contractions (3 in case group), Preterm Premature Rupture Of Membranes (PPROM) (4 in case group, 5 in control group), impaired renal function (1 in case group), meconium amniotic (1 in case group), vaginal blood loss (1 in case group, 1 in control group), preeclampsia (3 in case group), hypertension (2 in case group, 3 in control group), severe hypertension (1 in case group), postpartum hypertension (1 in control group), fever (2 in case group), postpartum fever (2 in control group), urinary tract infection (2 in case group), trauma (1 in case group), reduced signs of fetal life (2 in case group), back pain (1 in case group), tachycardia (1 in case group), gestational diabetes (2 in case group, 1 in control group), herpes gestationis (1 in case group), gestational pyelitis (1 in control group), pulmonary embolism (1 in control group), and positive discongruence (1 in control group).
Hb: hemoglobin; IQR: interquartile range; ICU: intensive care unit; IUGR: intrauterine growth retardation.